Novel Enzyme Technology for Food Applications (Hardcover)
by Robert Rastall

Product Details

• Hardcover: 336 pages
• Publisher: Woodhead Publishing Ltd (September 21, 2007)
• ISBN-10: 1845691326
• ISBN-13: 978-1845691325
• Product Dimensions: 9.2 x 6.2 x 1 inches
• Shipping Weight: 1.4 pounds

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Enzyme Systems that Metabolise Drugs and Other Xenobiotics
(Current Toxicology)
(Hardcover)
by Costas Ioannides

Editorial Reviews

Review
"an invaluable reference book" (ISSX Newsletter, Summer 2002)

Book Description
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include:
* enzyme function in the metabolism and bioactivation of xenobiotics
* substrate specificity
* tissue distribution
* species distribution (to include laboratory animals and humans)
* hormonal regulation
* sex differences
* modulation by prior exposure to other chemicals
* age-dependent expression
* pharmacogenetics and modulation by disease.
Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.

See all Editorial Reviews

Product Details

• Hardcover: 588 pages
• Publisher: Wiley; 1 edition (January 28, 2002)
• Language: English
• ISBN-10: 0471894664
• ISBN-13: 978-0471894667
• Product Dimensions: 9.5 x 6.2 x 1.4 inches
• Shipping Weight: 2.3 pounds

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Enzymes and Their Inhibitors
(Hardcover)
by H. John Smith (Editor), Claire Simons

Editorial Reviews

Review
value as a focused reference text for graduate students in pharmacology and enzymology. The various subjects are covered clearly and conciselywith adequate referencing, which should allow students to quickly obtain a broad overview of concepts in enzyme inhibitor development, and also to provide a window into more extensive literature in this area.
Journal of Medicinal Chemistry, 2005, volume 48

Book Description
In recent years the number of new drugs described as enzyme inhibitors has increased significantly. Once an enzyme target is selected or discovered for a particular disease or infection, detailed information must be compiled for the rational design of an inhibitor. Until now, a single handbook containing that crucial background information has not been available. Covering everything you need to know about this complex subject, Enzymes and Their Inhibition examines enzyme inhibition in detail, and describes the design and development of such inhibitors. Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition provides an overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss various types of enzyme inhibitors and the principles involved in developing them into effective drugs. Enzymes and Their Inhibition describes the problems that can be encountered in translating results from the bench to the market place, and suggests approaches that circumvent these difficulties. This outstanding text for students in pharmacology and medicinal chemistry is also a valuable professional reference.

Product Details

• Hardcover: 328 pages
• Publisher: CRC; 1 edition (July 15, 2004)
• Language: English
• ISBN-10: 0415334020
• ISBN-13: 978-0415334020
• Product Dimensions: 9.2 x 6.1 x 0.9 inches
• Shipping Weight: 1.3 pounds

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و عليكم السلام و رحمة الله و بركاته

يا اختي العزيزة بنت حيان ان احتجت لاي شئ أخر ما عليك الا ان تتصل بي
تحياتي الخاصة لك من جبار

بسم الله الرحمن الرحيم

All About Biochemistry

Guide to Biomolecular Simulations

ISBN: 1402035861
Title: Guide to Biomolecular Simulations (Focus on Structural Biology)
Author: Oren M. Becker Martin Karplus
Publisher: Springer
Publication Date: 2005-12-22
Number Of Pages: 220

Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures.
The widespread application of molecular dynamics and related methodologies suggests that it would be useful to have available an introductory self-contained course by which students with a relatively limited background in chemistry, biology and computer literacy, can learn the fundamentals of the field. This Guide to Biomolecular Simulations tries to fill this need. The Guide consists of six chapters which provide the fundamentals of the field and six chapters which introduce the reader to more specialized but important applications of the methodology.

Electron Paramagnetic Resonance in Biochemistry and Medicine

ISBN: 0306465310
Title: Electron Paramagnetic Resonance in Biochemistry and Medicine (Topics in Applied Chemistry)
Author: Rafik Galimzyanovich Sajfutdinov Lyudmila Ivanovna Larina Tamara Il'inichna Vakul'skaya Mikhail Grigor'evich Voronkov
Publisher: Springer
Publication Date: 2001-02
Number Of Pages: 284

Book Description
Electron Paramagnetic Resonance (EPR) spectroscopy -- also sometimes termed Electron Spin Resonance spectroscopy -- has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease.
EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations made possible by the introduction of spin labels, probes, and traps made EPR spectroscopy ever more applicable to biochemistry and medicine, to the point where in vivo studies are being carefully considered.

This comprehensive book discusses spectra of many tissues and bodily fluids, and the quantitative nature of paramagnetic centers in both normal individuals and patients suffering from a variety of diseases. Special attention is given to the EPR examination of bio-molecules, such as enzymes, polypeptides, vitamins, lipids, hydrocarbons, etc., which play an essential role in human activity.

This book will be of great interest to physicians specializing in many different areas. Similarly, biologists, biochemists, biophysicists, and chemists will find this book very useful. It has also been written so that it may be used as a textbook at graduate level.

Book Info
Irkutsk Medical Univ, Russia. Discusses spectra of many tissues and bodily fluids, and the quantitative and qualitative nature of paramagnetic centers in normal individuals and patients suffering from a variety of diseases. Special attention is given to the EPR examination

Protein Purification: Principles and Practice

ISBN: 0387940723
Title: Protein Purification: Principles and Practice
Author: R. K., Scopes Rk, Scopes
Publisher: Springer
Publication Date: 1993-11-01
Number Of Pages: 404

Book Description
The third edition of this classic guide to protein purification updates methods, principles and references. As in the widely-acclaimed earlier editions, Scopes guides both the novice and the experienced researcher from theory to application. Using the book, the reader is able to integrate methods effectively into optimum protocols for the task at hand. Reviews of earlier editions of Protein Purification described it as "good practical advice that is presented in a pleasantly readable form" (Analytical Biochemistry), "well organized and written clearly" (American Scientist), and "should be on every laboratory shelf where protein are being handled or purified...a feast and a genuine pleasure to read" (Nature).

Product Description
* 2 full volumes (1900 pages) of PDF-based two color text on a single CD-ROM, conveniently hyperlinked and indexed. Biochemistry CD-ROM is a convenient, desktop reference containing both volumes of the published book. It is a searchable and comprehensive reference.

The most comprehensive biochemistry text reference available on the market, organized into 32 chapters, 16 in each volume, containing the latest research in the field
Special features include boxed information on topics of general interest; study questions; tables of contents precedes each chapter; specialized chapters
CD ROM contains the complete text with hypertext linked index

Book Info
Iowa State Univ., Ames. Text is a comprehensive account of the chemical basis of life. Describes the complex structures in the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. Volume 1, c2001, listed in approval week 2001-16. Two-volume set not yet available

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Bioanalytical Chemistry

Product Description
Bioanalytical Chemistry provides a thorough introduction for students and practitioners with a broad range of backgrounds from chemistry to medicine. In so doing, it brings together many of the techniques commonly used by biochemists and molecular biologists. The text includes entire chapters on design and implementation of enzyme assays; mass spectrometry; and validation of new methods. Each chapter progresses from basic concepts to applications involving real samples, and ends with a set of problems, while an appendix contains selected answers. The authors have limited mathematical derivations to those that are essential for an understanding of each method and they include a list of suggested reading for further information. This textbook provides an ideal companion for students, researchers, and industrial scientists working in chemistry, biology, biochemistry, pharmacy, and medicine

Bioanalytical Chemistry, 2004-11

ISBN: 1860943705
Author: Andreas Manz, Nicole Pamme, Dimitri Iossifidis
Publisher: Imperial College Press
Publication Date: 2004-11
Number Of Pages: 201

Editorial Description
Interdisciplinary knowledge is becoming more and more important to the modern scientist. This invaluable textbook covers bioanalytical chemistry (mainly the analysis of proteins and DNA) and explains everything for the nonbiologist. Electrophoresis, mass spectrometry, biosensors, bioassays, DNA and protein sequencing are not necessarily all included in conventional analytical chemistry textbooks

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The Biology-Chemistry Interface: A Tribute to Koji Nakanishi




ISBN: 0824771168
Author: Koji Nakanishi
Publisher: Marcel Dekker
Publication Date: 1999-07-22
Number Of Pages: 512

Book Description
A tribute to the pioneering scientific work of Professor Koji Nakanishi, whose studies of natural products have effaced some of the conventional boundaries between biology and chemistry. It discusses an array of chromatographic separation methods and determination of structures on a microscale, analyzes bioassay-directed fractionation and other means of isolating biologically active compounds from plants and other sources, covers vital enzymes isolated from marine organisms such as algae, and more

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Principles of Biochemical Toxicology






Product Details

Book Description
Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following the acclaimed first two editions of Principles of Biochemical Toxicology, the author has expanded the text to include summary sections, questions and model answers and thoroughly revised artwork. These features, plus the new easy-to-read format, will make biochemical toxicology more accessible to undergraduates and postgraduates encountering the subject for the first time. This comprehensive textbook provides a thorough explanation of dose-response relationships, disposition and metabolism, toxic responses to foreign compounds and detailed examples to illustrate mechanisms of toxicity. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.


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Biochemistry: The Molecular Basis of Life





Product Details

Product Description

This textbook is intended for a diverse audience that ranges from chemistry majors to students in any of the life sciences. The logical organization (discussion of molecular structure immediately followed by the role it plays in metabolism) leads students through the complex world of biochemistry while an impressive art program helps to guide them through up-to-date concepts. Of special interest are the new Biochemical Methods boxes in the text, PowerPoint slides for instructors, and animated and annotated Chime structures of biomolecules in the OLC.



Book Info

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An Introduction to Computational Biochemistry









Product Details

Publisher: Wiley-Liss; 1st edition (April 30, 2002)
Language: English
ISBN-10: 047140120X
ISBN-13: 978-0471401209
Product Dimensions: 10 x 7.1 x 0.7 inches

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ISBN: 3527302441
Title: DNA Chromatography
Author: Douglas T. Gjerde
Publisher: Wiley-VCH

Summary:
This book describes a powerful and effective tool for the molecular biologist researcher. Readers will discover how DNA chromatography can be used in their own work. Intended as an introduction for the molecular biologist reader, this will also serve as a practical guide for the experienced user. The clear and concise writing style is also attractive to the chemist who wants to learn more about molecular biology

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Chemical Biology: Applications and Techniques

Hardcover: 272 pages
Publisher: Wiley; 1 edition (August 30, 2006)
Language: English
ISBN-10: 0470090642
ISBN-13: 978-0470090640
File type : PDF
File size : 4.1 MB

Book Description

This book provides an up-to-date guide to chemical biology. It is a modular textbook that brings together the tools and techniques used by physical scientists and makes them available to biological and biomedical scientists. Tools and techniques are explained at a suitable level and the book addresses topical chemical biology questions within each chapter.

Written by a team of international researchers and teachers at the cutting edge of chemical biology research, this book provides an exciting, comprehensive introduction to a wide range of chemical and physical techniques with applications in areas as diverse as molecular biology, signal transduction, drug discovery and medicine.
Techniques include: Cryo-electron microscopy, atomic force microscopy, differential scanning calorimetry in the study of lipid structures, membrane potentials and membrane probes, identification and quantification of lipids using mass spectroscopy, liquid state NMR, solid state NMR in biomembranes, molecular dynamics, two dimensional infra-red studies of biomolecules, single and two-photon fluorescence, optical tweezers, PET imaging and chemical genetics.

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Chemical Biology: Techniques and Applications will provide an invaluable resource for final year undergraduate and post graduate bioscience and biomedical students and pharmaceutical researchers with an interest in this fascinating, and ever changing field.

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Modern Experimental Biochemistry

Rodney F. Boyer
Paperback: 475 pages
Publisher: Prentice Hall; 3 edition (August 2, 2000)
Language: English
ISBN-10: 0805331115
ISBN-13: 978-0805331110

Table of Contents

I. THEORY AND EXPERIMENTAL TECHNIQUES. 1. Introduction to the Biochemistry Laboratory. 2. General Laboratory Procedures. 3. Purification and Identification of Biomolecules by Chromatography. 4. Characterization of Proteins and Nucleic Acids by Electrophoresis. 5. Spectroscopic Analysis of Biomolecules. 6. Radioisotopes in Biochemical Research. 7. Centrifugation in Biochemical Research. II. EXPERIMENTS. 1. Using the Computer in Biochemical Research. 2. Structural Analysis of a Dipeptide. 3. Using Gel Filtration to Study Ligand-Protein Interactions. 4. Isolation and Characterization of Bovine Milk—Lactalbumin. 5. Kinetic Analysis of Tyrosinase. 6. Purification and Characterization of Triacylglycerols in Natural Oils. 7. Identification of Serum Glycoproteins by SDS-PAGE and Western Blotting. 8. Isolation and Characterization of Plant Pigments. 9. Photoinduced Proton Transport through Chloroplast Membranes. 10. Isolation, Subfractionation, and Enzymatic Analysis of Beef Heart Mitochondria. 11. Measurement of Cholesterol and Vitamin C in Biological Samples. 12. Activity and Thermal Stability of Gel-immobilized Peroxidase. 13. Extraction and Characterization of Bacterial DNA. 14. Plasmid DNA Isolation and Characterization by Electrophoresis. 15. The Action of Restriction of Endonucleases on Plasmid or Viral DNA.

Oxford Dictionary of Biochemistry and Molecular Biology

ISBN: 0198506732
Publisher: Oxford University Press, USA
Publication Date: 2000-02-01
Number Of Pages: 672

Editorial Description
This book provides a survey of current biochemistry and molecular biology in the form of a dictionary. It contains short but informative entries arranged under more than 17,000 headwords, providing fundamental but up-to-date information that is often difficult to locate in today's overspecialized world. The book is intended as a handy reference of first resource for those seeking information outside their immediate knowledge area or for those who need to refresh their memory of fundamental

Enzyme Kinetics and Mechanisms
(Hardcover)
by Kenneth B. Taylor

Book Description
Enzyme Kinetics and Mechanisms takes the reader through the experimental techniques and the logic by which the mechanisms of enzyme-catalyzed reactions can be elucidated by the results of steady-state kinetics and related experiments. It is meant to make these investigations both satisfying and effective. In distinction to other available descriptions, the descriptions in enzyme Kinetics and Mechanisms are limited to more commonly utilized and useful models and techniques. The logic relating the chemical models to the mathematical models and the logic of relating the mathematical models to data is presented in rather concise text, figures and equations. The development of mathematical models from chemical models is done by a unique algorithm that is both simple and quick, and the same concept are utilized to develop models for the effects of a variety of reaction conditions on the initial velocity. In addition, the various relationships of data, mathematical models and the chemical models is illustrated with examples from the scientific literature.
Enzyme Kinetics and Mechanisms is intended for research workers, graduate students, post doctoral associates, and faculty in biochemistry and molecular biology who are interested in the techniques and logic by which mechanisms of enzymes-catalyzed reactions can be elucidated by investigation of steady-state kinetic experiments.
Product Details

Hardcover: 244 pages
Publisher: Springer; 1 edition
(June 30, 1991)
Language: English
ISBN-10: 1402007280
ISBN-13: 978-1402007286
Product Dimensions: 10 x 6.3 x 0.7 inches
Shipping Weight: 1.2 pounds


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