Book Properties
ISBN: 3527304053
Title: Peptides: Chemistry and Biology
Author: Norbert Sewald
Publisher: Wiley-VCH
Publication Date: 2002-09-09
Number Of Pages: 590 PDF


Review

The book by Sewald and Jakubke is most timely and will be extremely useful for students and researchers in peptide science. The authors address the broad fundamentals of peptide synthesis and structure. They also identify important families of biologically active peptides.
Lastly, they bring their impressive treatment up to the most current of peptide activities including pseudopeptides, peptidomimetics, combinatorial syntheses and applications of peptides as pharmaceuticals and in biotechnology. The book is an impressive addition to the field and will help researchers identify peptide derivatives as key target molecules for pharmaceuticals and novel structures in biotechnology. - Murray Goodman, Univ. of California, San Diego

"...absolutely excellent book, handsomely produced and underpriced..."(European Peptide Society Newsletter, 1 January 2003)

Book Description

Peptides play a decisive role in many physiological processes, whether as neurotransmitters, hormones or antibiotics. The rapid developments in peptide research over the past few decades make it almost impossible for newcomers to gain an overview. This means an easily comprehensible yet concise introduction is vital.

This unique work covers all the important aspects of this wide-ranging field in one handy volume. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides, via chemical, biochemical and genetic methods of peptide synthesis, right up to peptide libraries, peptide design and their role in drug research. Yet this book offers much more than a mere overview of the latest level of research. An encyclopedic appendix with valuable data on more than 500 biological relevant peptides and proteins, a comprehensive register and details of further literature references make this the ideal reference for all questions regarding peptide research. For newcomers and specialists alike.

Table of Contents

Preface
Abbreviations
1 Introduction and Background 1
2 Fundamental Chemical and Structural Principles 5
3 Biologically Active Peptides 61
4 Peptide Synthesis 135
5 Synthesis Concepts for Peptides and Proteins 269
6 Synthesis of Special Peptides and Peptides and Peptide Conjugates 311
7 Peptide and Protein Design, Pseudopeptides, and Peptidomimetics 339
8 Combinatorial Peptide Synthesis 379
9 Application of Peptides and Proteins 403
Glossary 429
Index 545