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الكتاب الاول

An Introduction to Medicinal Chemistry

Graham L. Patrick, "An Introduction to Medicinal Chemistry"
Oxford University Press, USA; | ISBN-10: 0199275009 | 768 pages | PDF | 10,4 Mb

Review: `Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' Chemistry and Industry 2002

`"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' Stuart Warriner, University of Leeds, 2004

Book Description
Many of us think nothing of taking a painkiller to ease a headache, or to relieve the symptoms of 'flu. But how do drugs have their effect in the human body? How are new drugs discovered and designed to be as effective as possible? An Introduction to Medicinal Chemistry offers an engaging insight into the one field of chemistry that arguably has the greatest impact on our quality of life than any other. Newly structured into four parts, the book opens in Part A with an introduction to pharmacodynamics and pharmacokinetics. Pharmacodynamics considers the types of molecular targets used by drugs, the interactions which are involved when a drug meets that target, and the consequences of those interactions. Pharmacokinetics considers the issues involved in a drug reaching its target in the first place. Part B goes on to examine the general principles and strategies involved in discovering and designing new drugs and developing them for the marketplace, while Part C looks at particular 'tools of the trade' which are invaluable in those processes. Finally, Part D covers a selection of specific topics within medicinal chemistry. Reflecting a change in emphasis in medicinal chemistry research, this Part takes us from the largely trial-and-error approach to drug design to the rational approach, and explores the most recent advances in molecular biology and genetics which have revolutionised drug design. With a striking new two-colour text design, and greatly enriched learning features, the third edition conveys the fascination of working in a field which overlaps the disciplines of chemistry, biochemistry, physiology, microbiology, cell biology, and pharmacology. A must-have textbook for any student of medicinal chemistry. Online Resource Centre - Figures available to download, to facilitate lecture preparation - 3D molecular structures, to enable students to visualise key structures in an interactive way - Multiple choice questions with answers, to support and encourage independent learning

الكتاب الثاني

Introduction to Medicinal Chemistry: How Drugs Act and Why

Alex Gringauz, " Introduction to Medicinal Chemistry: How Drugs Act and Why "
Wiley-VCH; 1 edition | ISBN-10: 0471185450 | 736 Pages | Djvu | 22,3 Mb

Book Description:

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.

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